Helicobacter Stool Antigen Test

Looks for Helicobacter pylori antigen in stool. A detected result can support evidence of current H. pylori infection, while medicines, collection timing and sample quality can affect the result.

At a glance

• Sample: Stool
• Collection: Collect a stool sample at home using TDL self-collect kit KT363 or KT472
• Estimated turnaround: 3 days from laboratory receipt of a usable sample

What this test measures

H. pylori antigen

Material associated with Helicobacter pylori in stool, used to look for evidence of current infection. A detected result supports current H. pylori infection. A negative result can be unreliable after certain antibiotics, bismuth or acid-suppressing medicines.

How clinicians use this test

Clinicians use H. pylori antigen as part of investigating digestive symptoms or monitoring a known condition. The result may narrow the possibilities, but history, examination and other tests may still be needed for diagnosis.

Is this the right test for you?

Someone exploring the stated digestive marker with a clinician, provided urgent or persistent symptoms are not being delayed by postal testing.

Preparation and collection

Follow the supplied stool-collection instructions and return the sample on the same day. Do not post over weekends or bank holidays. Medicines can affect stool-antigen results, so check the kit instructions or ask a clinician about timing before collection.

Understanding your result

The laboratory will report H. pylori antigen with an assay-specific reference range, threshold or qualitative interpretation. Read the biomarker explanation above for common reasons a result may be high, low, detected or reactive, then use the laboratory comment and clinical context to decide whether repeat or follow-up testing is needed.

Your results and next steps

Discuss a raised, detected or otherwise unexpected result with a GP or digestive-health clinician. Persistent symptoms, bleeding, weight loss or worsening pain need assessment even when the result is reassuring.

Limitations

A result cannot identify every cause of digestive symptoms. Collection quality, medicines, recent infection and other conditions may affect interpretation.

When to get medical help

Do not wait for a home-test result if you feel seriously unwell. Call 999 for a life-threatening emergency, or use NHS 111 when you need urgent advice and are unsure what to do.